In the process of CO2 flooding production and oil lifting,with the decrease of pressure,a large amount of associated gas will be separated from the produced liquid. In the associated gas,the content of CO2 is as high as 50%-90%. Compared with CH4,gaseous CO2 has a stronger throttling cooling effect,which may cause the generation of hydrate to block the pipeline,threatening the operation safety of the gathering and transportation system. The influence of CO2 content on the CO2-CH4 gas throttling and hydrate generation characteristics was studied using a high-pressure sapphire reactor. The results show that:When the initial pressure is high (16 MPa),the throttling effect coefficient Di of the mixture gas with the same CO2 proportion is about 1.3-5.4 ℃/MPa,and the incorporation of CH4 will enhance the throttling effect of the mixture gas,indicating that the high pressure section is mainly affected by the throttling effect of CH4;when the initial pressure is low (5 MPa,4 MPa),the throttling effect coefficient Di is about 3.4-11.9 ℃/MPa,and the incorporation of CH4 will weaken the throttling effect of the mixture gas,indicating that the low pressure section is mainly affected by the throttling effect of gaseous CO2. The higher the pressure at which CO2-CH4 gases with the same CO2 content are,the higher the temperature at which hydrates are generated,and the easier it is to generate hydrates. At the same pressure,the lower the CO2 content is,the lower the temperature at which hydrates are formed. When the CO2 content is 8%-100% and the pressure is 1.5-5 MPa,the hydrate generation temperature is 0.5~10 ℃. The comparison results between the experimental and software simulation data show that the PR equation of state has a high correlation for the calculation of CO2-CH4 throttling and hydrate generation characteristics. The research results can provide a reference for the selection of safe gathering and transportation process parameters.